Opportunity Information: Apply for RFA DK 19 504
This opportunity is a National Institutes of Health (NIH) cooperative agreement (U01, clinical trial optional) that uses a limited competition to fund a single Coordination and Data Management Center (CDMC) for the Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer (CPDPC). The purpose is to continue and finish the consortiums ongoing, multi-site research program focused on chronic pancreatitis (CP) and the factors that drive pancreatic cancer risk in several high-risk patient groups, including children and adults with CP (including acute recurrent pancreatitis, ARP), individuals with pancreatogenic or type 3c diabetes (T3cDM), and patients with newly diagnosed diabetes who may have an elevated risk of pancreatic cancer. Because it is a U01 cooperative agreement, the work is expected to be carried out in close coordination with NIH program staff and in active partnership with the other consortium awardees rather than as a fully independent investigator-initiated project.
The CPDPC has been operating since Fall 2015 and has built a large, longitudinal clinical research platform with deep epidemiologic and biologic characterization of participants. Through this infrastructure, the consortium studies the natural history and underlying biology of chronic pancreatitis and its major downstream complications, such as chronic pain, pancreatic exocrine insufficiency, and progression to type 3c diabetes. A major theme is clarifying the relationship between diabetes and pancreatic cancer, including research on pancreatic cancer development in people with newly diagnosed diabetes. This CDMC award is intended to keep the consortium functioning as an integrated network so these long-running studies can be completed and their data harmonized, curated, and analyzed in a consistent, high-quality way.
Functionally, the CDMC serves as the operational backbone of the consortium. While the FOA text provided does not list every task line-by-line, a CDMC in this setting is generally responsible for consortium-wide coordination, data standards and governance, study operations support, and centralized data management across multiple Clinical Centers (CCs). That includes developing and maintaining common data elements and case report forms, managing databases and secure data flows, supporting regulatory and data sharing processes, coordinating communications and meetings, tracking enrollment and study milestones, overseeing data quality control, and enabling pooled analyses that rely on standardized definitions and harmonized biospecimen and clinical data. The FOA also makes clear that the CDMC and the Clinical Centers are expected to share results freely within the consortium and to continue trans-consortium collaborative projects that leverage the combined expertise and technology across member sites, with ongoing projects referenced through the CPDPC clinical studies listings.
This FOA is paired with a separate solicitation for the consortium Clinical Centers (referenced as RFA-DK-19-009). In other words, the network is structured around multiple Clinical Centers that recruit and follow participants and conduct protocol-driven assessments, plus one centrally funded CDMC that coordinates and manages the shared data and cross-site operations. The limited competition language signals that the NIH is not opening this to the general community as an unrestricted call; it is designed to support continuation of an existing, defined consortium structure and to ensure a single, consistent coordinating hub.
Eligibility is restricted. The opportunity lists eligible applicants as public and state-controlled institutions of higher education, and it explicitly states that non-U.S. (foreign) institutions are not eligible to apply, and that non-U.S. components of U.S. organizations are also not eligible to apply. At the same time, it allows foreign components as defined in the NIH Grants Policy Statement, which typically means a U.S. applicant organization may, under NIH rules and with appropriate justification and oversight, include certain foreign activities or collaborations as components of the project even though a foreign institution cannot be the prime applicant. Applicants are directed to the full announcement for details and definitions.
Key administrative details from the source information include the Funding Opportunity Number RFA-DK-19-504, the NIH as the issuing agency, a cooperative agreement funding instrument, and activity categories aligned with health and related areas. The original closing date listed is 2019-12-17, and the FOA anticipates one award (a single CDMC). The announcement was created on 2019-09-26. The CFDA program numbers associated with the opportunity are 93.393, 93.399, and 93.847. The award ceiling and expected dollar amounts are not specified in the text you provided, so applicants would need to consult the full FOA for budget limits, project period, and detailed scope and review criteria.Apply for RFA DK 19 504
- The National Institutes of Health in the education, food and nutrition, health sector is offering a public funding opportunity titled "Limited Competition: Continuation of the Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Coordination and Data Management Center (CPDPC-CDMC) (U01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393, 93.399, 93.847.
- This funding opportunity was created on 2019-09-26.
- Applicants must submit their applications by 2019-12-17. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education.
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